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ADAM 17‐mediated CD 44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC

ADAM 17‐mediated CD 44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2299117130

ADAM 17‐mediated CD 44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC

About this item

Full title

ADAM 17‐mediated CD 44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC

Publisher

Bognor Regis: John Wiley & Sons, Inc

Journal title

Cancer medicine (Malden, MA), 2013-12, Vol.2 (6), p.793-802

Language

English

Formats

Publication information

Publisher

Bognor Regis: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

CD
44, an extracellular matrix (
ECM
) receptor, has been described as a cancer stem cell marker in multiple cancers, including head and neck squamous cell carcinoma (
HNSCC
).
HNSCC
orasphere formation or stemness was characterized by cleavage of
CD
44, and thus we hypothesized that this proteolytic processing may be cri...

Alternative Titles

Full title

ADAM 17‐mediated CD 44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2299117130

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2299117130

Other Identifiers

ISSN

2045-7634

E-ISSN

2045-7634

DOI

10.1002/cam4.147

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