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A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2300817249

A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

About this item

Full title

A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Enhancers that are conserved deep in evolutionary time regulate characteristics held in common across taxonomic classes. Here, we deleted the highly conserved Shh enhancer SBE2 (Shh brain enhancer 2) which markedly reduced expression within the embryonic brain specifically in the rostral diencephalon; however, a putative secondary enhancer driving...

Alternative Titles

Full title

A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2300817249

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2300817249

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/794198