Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53
Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
TP53
is the most frequently mutated gene in human cancer, whereas tumors with wild-type
TP53
develop alternative strategies to survive. Identifying new regulators of p53 reactivation would greatly contribute to the development of cancer therapies. After screening the entire genome in liver cancer cells, we identified lysyl oxidase-like 4 (...
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Full title
Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53
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TN_cdi_proquest_journals_2300955220
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2300955220
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-019-0293-x
