Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat...
Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Background
Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We identified the expression of a G protein-coupled receptor, Gpr17, in the ARH and hypothesized that it contributes to the regulato...
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Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding
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TN_cdi_proquest_journals_2305536757
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2305536757
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E-ISSN
2044-4052
DOI
10.1038/s41387-019-0096-7
