Synthesis and crystal structure of trifluoromethyl-containing bendamustine hydrochloride
Synthesis and crystal structure of trifluoromethyl-containing bendamustine hydrochloride
About this item
Full title
Author / Creator
Yin, Yue , Liu, Huailiang , Xiao, Tangxin , Sun, Xiaoqiang , Yang, Ke and Li, Zhengyi
Publisher
London, England: SAGE Publications
Journal title
Language
English
Formats
Publication information
Publisher
London, England: SAGE Publications
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Scope and Contents
Contents
A simple strategy to afford trifluoromethyl-containing bendamustine hydrochloride in 34% overall via nine simple steps including substitution, selective reduction, N-acylation, cyclization, esterification, nitro-reduction, N-dihydroxyethylation, chlorination, and acid-catalyzed hydrolysis from commercially available 2,4-dinitrochlorobenzene is desc...
Alternative Titles
Full title
Synthesis and crystal structure of trifluoromethyl-containing bendamustine hydrochloride
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Author / Creator
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Record Identifier
TN_cdi_proquest_journals_2306446262
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2306446262
Other Identifiers
ISSN
1747-5198
E-ISSN
2047-6507
DOI
10.1177/1747519819868202
