Cohesin depleted cells rebuild functional nuclear compartments after endomitosis
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Cohesin plays an essential role in chromatin loop extrusion, but its impact on a compartmentalized nuclear architecture, linked to nuclear functions, is debatable. Using live-cell and super-resolved 3D microscopy, we demonstrate that cohesin depleted cells pass through an endomitosis and rebuild a single multilobulated nucleus (MLN) with c...
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Cohesin depleted cells rebuild functional nuclear compartments after endomitosis
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TN_cdi_proquest_journals_2308330302
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2308330302
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E-ISSN
2692-8205
DOI
10.1101/816611
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https://www.proquest.com/docview/2308330302?pq-origsite=primo&accountid=13902
