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The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation

The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2310139091

The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation

About this item

Full title

The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

CD4+ T helper (Th) cell differentiation is controlled by lineage-specific expression of transcription factors and effector proteins, as well as silencing of lineage-promiscuous genes. Lysine methyltransferases (KMTs) comprise a major class of epigenetic enzymes that are emerging as important regulators of Th cell biology. Here, we show that the KMT...

Alternative Titles

Full title

The lysine methyltransferase DOT1L controls CD4+ T cell-dependent immunity and inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2310139091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2310139091

Other Identifiers

DOI

10.1101/821348