Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering
Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Single-cell transcriptomics has sensitivity limits that restrict low abundance transcript identification, affects clustering and introduce artefact. Here, we describe Constellation DropSeq (C-DropSeq), a molecular transcriptome filter that delivers two orders of magnitude sensitivity gains by maximising read utility while reducing sequencing depth...
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Full title
Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering
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TN_cdi_proquest_journals_2312411708
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2312411708
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E-ISSN
2692-8205
DOI
10.1101/800631
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https://www.proquest.com/docview/2312411708?pq-origsite=primo&accountid=13902