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Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering

Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2312411708

Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering

About this item

Full title

Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Single-cell transcriptomics has sensitivity limits that restrict low abundance transcript identification, affects clustering and introduce artefact. Here, we describe Constellation DropSeq (C-DropSeq), a molecular transcriptome filter that delivers two orders of magnitude sensitivity gains by maximising read utility while reducing sequencing depth...

Alternative Titles

Full title

Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2312411708

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2312411708

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/800631