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Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepat...

Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2312543602

Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma

About this item

Full title

Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2019-11, Vol.38 (45), p.7035-7045

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Metformin is a hypoglycaemic agent used to treat type 2 diabetes mellitus (DM2) patients, with a broad safety profile. Since previous epidemiological studies had shown that the incidence of hepatocellular carcinoma (HCC) decreased significantly in metformin treated DM2 patients, we hypothesised that intervention with metformin could reduce the risk...

Alternative Titles

Full title

Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2312543602

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2312543602

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-019-0942-z

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