Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAV...
Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS
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Author / Creator
Wang, Yao , Yuan, Shaochun , Jia, Xin , Ge, Yong , Ling, Tao , Nie, Meng , Lan, Xihong , Chen, Shangwu and Xu, Anlong
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In the past two decades, emerging studies have suggested that DExD/H box helicases belonging to helicase superfamily 2 (SF2) play essential roles in antiviral innate immunity. However, the antiviral functions of helicase SF1, which shares a conserved helicase core with SF2, are little understood. Here we demonstrate that zinc finger NFX1-type conta...
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Full title
Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS
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Record Identifier
TN_cdi_proquest_journals_2312790785
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2312790785
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-019-0416-0
