Enhancers predominantly regulate gene expression in vivo via transcription initiation
Enhancers predominantly regulate gene expression in vivo via transcription initiation
About this item
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Author / Creator
Larke, Martin Sc , Nojima, Taka , Telenius, Jelena M , Sharpe, Jacqueline A , Stanley, Jacqueline A , Butler, Susan , Beagrie, Robert A , Downes, Damien J , Schwessinger, Ron , Oudelaar, Marieke , Truch, Julia , Crompton, Bryony , Bender, Michael A , Proudfoot, Nicholas J , Higgs, Douglas R and Hughes, Jim Raymond
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Gene transcription occurs via a cycle of linked events including initiation, promoter proximal pausing and elongation of RNA polymerase II (Pol II). A key question is how do transcriptional enhancers influence these events to control gene expression? Here we have used a new approach to quantify transcriptional initiation and pausing in vivo, while...
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Full title
Enhancers predominantly regulate gene expression in vivo via transcription initiation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_journals_2314860695
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2314860695
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/844191
How to access this item
https://www.proquest.com/docview/2314860695?pq-origsite=primo&accountid=13902
