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Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2314997667

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

About this item

Full title

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Dense surface glycosylation on the HIV-1 envelope (Env) protein acts as a shield from the adaptive immune system. However, the molecular complexity and flexibility of glycans make experimental studies a challenge. Here we have integrated high-throughput atomistic modeling of fully glycosylated HIV-1 Env with graph theory to capture immunologically...

Alternative Titles

Full title

Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2314997667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2314997667

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/846071