Mutant GNLY is linked to Stevens–Johnson syndrome and toxic epidermal necrolysis
Mutant GNLY is linked to Stevens–Johnson syndrome and toxic epidermal necrolysis
About this item
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous adverse reactions to drugs. Granulysin (GNLY) plays a key role in keratinocyte apoptosis during SJS/TEN pathophysiology. To determine if GNLY-encoding mutations might be related to the protein’s functional disturbances, contributing to SJS/TEN pathogenesis...
Alternative Titles
Full title
Mutant GNLY is linked to Stevens–Johnson syndrome and toxic epidermal necrolysis
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TN_cdi_proquest_journals_2316975508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2316975508
Other Identifiers
ISSN
0340-6717
E-ISSN
1432-1203
DOI
10.1007/s00439-019-02066-w
