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Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2319253854

Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

About this item

Full title

Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2019-11, Vol.381 (22), p.2176-2178

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

An infant with SAM-like syndrome (severe dermatitis, allergies, and metabolic wasting) was found to have a substantial increase in the number of T-helper 17 cells. Administration of the monoclonal antibody secukinumab produced remarkable improvement, with symptom relief and restoration of normal growth.

Alternative Titles

Full title

Imbalance in T-Helper 17 Cells and Targeted Therapy in an Infant with SAM-like Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2319253854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2319253854

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMc1908531

How to access this item