Targeted protein degradation: expanding the toolbox
Targeted protein degradation: expanding the toolbox
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Proteolysis-targeting chimeras (PROTACs) and related molecules that induce targeted protein degradation by the ubiquitin–proteasome system represent a new therapeutic modality and are the focus of great interest, owing to potential advantages over traditional occupancy-based inhibitors with respect to dosing, side effects, drug resistance and modul...
Alternative Titles
Full title
Targeted protein degradation: expanding the toolbox
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_journals_2319482776
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2319482776
Other Identifiers
ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-019-0047-y
