Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-...
Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
B-cell precursor (BCP) ALL carry a variety of classical V(D)J rearrangements as well as genomic fusions and translocations. Here, we assessed the value of genomic capture high-throughput sequencing (gc-HTS) in BCP ALL (
n
= 183) for the identification and implementation of targets for minimal residual disease (MRD) testing. For TRδ, a total...
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Full title
Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL
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TN_cdi_proquest_journals_2319731520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2319731520
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ISSN
2044-5385
E-ISSN
2044-5385
DOI
10.1038/s41408-019-0257-x
