Phase 3 Efficacy Analysis of a Typhoid Conjugate Vaccine Trial in Nepal
Phase 3 Efficacy Analysis of a Typhoid Conjugate Vaccine Trial in Nepal
About this item
Full title
Author / Creator
Shakya, Mila , Colin-Jones, Rachel , Theiss-Nyland, Katherine , Voysey, Merryn , Pant, Dikshya , Smith, Nicola , Liu, Xinxue , Tonks, Susan , Mazur, Olga , Farooq, Yama G , Clarke, Jenny , Hill, Jennifer , Adhikari, Anup , Dongol, Sabina , Karkey, Abhilasha , Bajracharya, Binod , Kelly, Sarah , Gurung, Meeru , Baker, Stephen , Neuzil, Kathleen M , Shrestha, Shrijana , Basnyat, Buddha , Pollard, Andrew J and TyVAC Nepal Study Team
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Typhoid remains a major cause of illness and death globally. In this trial, the efficacy of a typhoid conjugate vaccine was assessed in children in Nepal. A total of 20,019 children were randomly assigned to receive either a TCV or a meningococcal A vaccine. The TCV was associated with a decrease of 81.6% in
Salmonella
Typhi bacteremia.
Alternative Titles
Full title
Phase 3 Efficacy Analysis of a Typhoid Conjugate Vaccine Trial in Nepal
Authors, Artists and Contributors
Author / Creator
Colin-Jones, Rachel
Theiss-Nyland, Katherine
Voysey, Merryn
Pant, Dikshya
Smith, Nicola
Liu, Xinxue
Tonks, Susan
Mazur, Olga
Farooq, Yama G
Clarke, Jenny
Hill, Jennifer
Adhikari, Anup
Dongol, Sabina
Karkey, Abhilasha
Bajracharya, Binod
Kelly, Sarah
Gurung, Meeru
Baker, Stephen
Neuzil, Kathleen M
Shrestha, Shrijana
Basnyat, Buddha
Pollard, Andrew J
TyVAC Nepal Study Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2321787687
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2321787687
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1905047
