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Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a...

Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2324512188

Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a novel mechanism in multiple sclerosis pathogenesis

About this item

Full title

Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a novel mechanism in multiple sclerosis pathogenesis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Multiple sclerosis (MS) is a neuro-inflammatory disease for which the pathogenesis remains largely unclear. Lysophosphatidic acid (LPA) is an endogenous phospholipid that is involved in multiple immune cell functions and is dysregulated in MS. Its receptor LPA1 is expressed in macrophages and regulates their activation, which is of interest due to...

Alternative Titles

Full title

Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a novel mechanism in multiple sclerosis pathogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2324512188

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2324512188

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/870980