Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequenc...
Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair derived artifacts as residual errors
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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To improve the accuracy and the cost-efficiency of next-generation sequencing in ultralow-frequency mutation detection, we developed the Paired-End and Complementary Consensus Sequencing (PECC-Seq), a PCR-free duplex consensus sequencing approach. PECC-Seq employed shear points as endogenous barcodes to identify consensus sequences from the overlap...
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Full title
Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair derived artifacts as residual errors
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TN_cdi_proquest_journals_2329992511
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2329992511
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E-ISSN
2692-8205
DOI
10.1101/2019.12.22.886440
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https://www.proquest.com/docview/2329992511?pq-origsite=primo&accountid=13902
