Dosing optimization of CCR 4 immunotoxin for improved depletion of CCR 4 + Treg in nonhuman primates
Dosing optimization of CCR 4 immunotoxin for improved depletion of CCR 4 + Treg in nonhuman primates
About this item
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Author / Creator
Publisher
Hoboken: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley & Sons, Inc
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More information
Scope and Contents
Contents
Recently, we have developed a diphtheria toxin‐based recombinant anti‐human
CCR
4 immunotoxin for targeting
CCR
4
+
tumors and Tregs. In this study, we further optimized the dosing schedule for improved
CCR
4
+
Treg depletion. We have demonstrated that up to a 90% depletion was achieved and the depletion extended to ap...
Alternative Titles
Full title
Dosing optimization of CCR 4 immunotoxin for improved depletion of CCR 4 + Treg in nonhuman primates
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TN_cdi_proquest_journals_2331409230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331409230
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12331
