MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation
MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation
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Kidlington: Elsevier Limited
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English
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Kidlington: Elsevier Limited
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EssentialsMMP‐13 has the potential to influence platelet function and thrombus formation directly.We sought to elucidate whether MMP‐13 is able to bind to specific platelet receptors.MMP‐13 is able to bind to platelet alphaIIbbeta3 (αIIbβ3) and glycoprotein (GP)VI.These interactions are sufficient to inhibit platelet aggregation and thrombus format...
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MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation
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TN_cdi_proquest_journals_2331416160
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331416160
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E-ISSN
2475-0379
DOI
10.1002/rth2.12088