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MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation

MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331416160

MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation

About this item

Full title

MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation

Publisher

Kidlington: Elsevier Limited

Journal title

Research and practice in thrombosis and haemostasis, 2018-04, Vol.2 (2), p.370-379

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Limited

More information

Scope and Contents

Contents

EssentialsMMP‐13 has the potential to influence platelet function and thrombus formation directly.We sought to elucidate whether MMP‐13 is able to bind to specific platelet receptors.MMP‐13 is able to bind to platelet alphaIIbbeta3 (αIIbβ3) and glycoprotein (GP)VI.These interactions are sufficient to inhibit platelet aggregation and thrombus format...

Alternative Titles

Full title

MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2331416160

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331416160

Other Identifiers

E-ISSN

2475-0379

DOI

10.1002/rth2.12088

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