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Cell shape, and not 2D migration, predicts ECM-driven 3D cell invasion in breast cancer

Cell shape, and not 2D migration, predicts ECM-driven 3D cell invasion in breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331695612

Cell shape, and not 2D migration, predicts ECM-driven 3D cell invasion in breast cancer

About this item

Full title

Cell shape, and not 2D migration, predicts ECM-driven 3D cell invasion in breast cancer

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Metastasis, the leading cause of death in cancer patients, requires the invasion of tumor cells through the stroma in response to migratory cues, such as those provided by the extracellular matrix (ECM). Recent advances in proteomics have led to the identification of hundreds of ECM proteins which are more abundant in tumors relative to healthy tis...

Alternative Titles

Full title

Cell shape, and not 2D migration, predicts ECM-driven 3D cell invasion in breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2331695612

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331695612

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2019.12.31.892091