Recurrent pre-leukemic deletions in myeloid malignancies are the result of DNA double-strand breaks...
Recurrent pre-leukemic deletions in myeloid malignancies are the result of DNA double-strand breaks followed by microhomology-mediated end joining
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
The mechanisms underlying myeloid malignancies deletions are not well understood, nor is it clear why specific genomic hotspots are predisposed to particular deletions. In the current study we inspected the genomic regions around recurrent deletions in myeloid malignancies, and identified microhomology-mediated end-joining (MMEJ) signatures in recu...
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Full title
Recurrent pre-leukemic deletions in myeloid malignancies are the result of DNA double-strand breaks followed by microhomology-mediated end joining
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TN_cdi_proquest_journals_2331918903
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2331918903
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E-ISSN
2692-8205
DOI
10.1101/2020.01.01.888610
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https://www.proquest.com/docview/2331918903?pq-origsite=primo&accountid=13902
