Interruption of thymic activity in adults improves responses to tumor immunotherapy
Interruption of thymic activity in adults improves responses to tumor immunotherapy
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
The thymus produces precursors of both effectors and regulatory T cells (Tconv and Treg, respectively) whose interactions prevents autoimmunity while allowing efficient protective immune responses. Tumors express a composite of self- and tumor-specific antigens and engage both Tconv and Treg cells. Along the aging process, the thymus involutes, and...
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Full title
Interruption of thymic activity in adults improves responses to tumor immunotherapy
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TN_cdi_proquest_journals_2334874286
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2334874286
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E-ISSN
2692-8205
DOI
10.1101/2020.01.08.899484
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https://www.proquest.com/docview/2334874286?pq-origsite=primo&accountid=13902
