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The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essen...

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2335759656

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virus

About this item

Full title

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virus

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The positive stranded RNA genomes of picornaviruses comprise a single large open reading frame flanked by 5′ and 3′ untranslated regions (UTRs). Foot-and-mouth disease virus (FMDV) has an unusually large 5′ UTR (1.3 kb) containing five structural domains. These include the internal ribosome entry site (IRES), which facilitates initiation of transla...

Alternative Titles

Full title

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2335759656

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2335759656

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.01.10.901801