Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex
Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Rad4/XPC is a key DNA damage sensor for nucleotide excision repair (NER) in eukaryotes. Rad4/XPC recognizes diverse bulky lesions by flipping out two lesion-containing nucleotide pairs and inserting a β-hairpin from the BHD3 domain (β-hairpin3) into the DNA duplex. We have previously observed that Rad4 can form the same ′open′ structure when covale...
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Full title
Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex
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TN_cdi_proquest_journals_2340210687
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2340210687
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E-ISSN
2692-8205
DOI
10.1101/2020.01.16.909549
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https://www.proquest.com/docview/2340210687?pq-origsite=primo&accountid=13902
