Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitoc...
Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitochondrial pyruvate availability
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Greece: Spandidos Publications
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Language
English
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Publisher
Greece: Spandidos Publications
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Scope and Contents
Contents
The aim of the present study was to investigate the metabolic and anticancer effects of troglitazone (TGZ) with a focus on the potential role of mitochondrial pyruvate utilization. 2‑Deoxyglucose (2‑DG) was more cytotoxic in CT26 cancer cells compared with T47D cells, despite a smaller suppression of glucose uptake. On the other hand, TGZ caused a...
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Full title
Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitochondrial pyruvate availability
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TN_cdi_proquest_journals_2342202207
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2342202207
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ISSN
1021-335X
E-ISSN
1791-2431
DOI
10.3892/or.2019.7436
