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MAPK-induced miR-29 targets MAFG and suppresses melanoma development

MAPK-induced miR-29 targets MAFG and suppresses melanoma development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2347062938

MAPK-induced miR-29 targets MAFG and suppresses melanoma development

About this item

Full title

MAPK-induced miR-29 targets MAFG and suppresses melanoma development

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

ABSTRACT The tumor suppressive miR-29 family of microRNAs is encoded by two clusters, miR-29b1∼a and miR-29b2∼c, and is regulated by several oncogenic and tumor suppressive stimuli. Here we investigated whether oncogenic MAPK hyperactivation regulates miR-29 abundance and how this signaling axis impacts melanoma development. Using mouse embryonic f...

Alternative Titles

Full title

MAPK-induced miR-29 targets MAFG and suppresses melanoma development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2347062938

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2347062938

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.01.27.922153