SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
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Author / Creator
Smeester, Branden A. , Slipek, Nicholas J. , Pomeroy, Emily J. , Bomberger, Heather E. , Shamsan, Ghaidan A. , Peterson, Joseph J. , Crosby, Margaret R. , Draper, Garrett M. , Becklin, Kelsie L. , Rahrmann, Eric P. , McCarthy, James B. , Odde, David J. , Wood, David K. , Largaespada, David A. and Moriarity, Branden S.
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Semaphorins, specifically type IV, are important regulators of axonal guidance and have been increasingly implicated in poor prognoses in a number of different solid cancers. In conjunction with their cognate PLXNB family receptors, type IV members have been increasingly shown to mediate oncogenic functions necessary for tumor development and malig...
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Full title
SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
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TN_cdi_proquest_journals_2348284517
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2348284517
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-1041-x