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Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2348540935

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

About this item

Full title

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The extracellular matrix (ECM) is a major component of the tumor microenvironment that supports cellular growth, promotes local invasion from the primary tumor, and contributes to metastatic outgrowth in sites of colonization. Obesity is a systemic disease that causes chronic inflammation which can lead to ECM deposition and ultimately fibrosis in...

Alternative Titles

Full title

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2348540935

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2348540935

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.01.29.924431