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Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2352508186

Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

About this item

Full title

Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

It is challenging to predict the impact of small genetic changes such as single nucleotide polymorphisms on gene expression, since mechanisms involved in gene regulation and their cis-regulatory encoding are not well-understood. Recent studies have attempted to predict the functional impact of non-coding variants based on available knowledge of cis...

Alternative Titles

Full title

Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2352508186

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2352508186

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.02.07.939264