Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib
Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib
About this item
Full title
Author / Creator
Wang, Zehua , Gao, Jianwen , Ohno, Yuko , Liu, Haiou and Xu, Congjian
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
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Scope and Contents
Contents
Objective
Senescence mechanisms are vital to resistance to long-term olaparib maintenance treatment. Recently, peroxisome proliferator-activated receptor-γ agonists (e.g., rosiglitazone) have been reported to ameliorate the senescence-like phenotype by modulating inflammatory mediator production. This study examined synergistic effects on the an...
Alternative Titles
Full title
Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib
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Author / Creator
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Record Identifier
TN_cdi_proquest_journals_2353920820
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2353920820
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-019-04025-8