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Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib

Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2353920820

Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib

About this item

Full title

Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2020-02, Vol.85 (2), p.273-284

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Objective
Senescence mechanisms are vital to resistance to long-term olaparib maintenance treatment. Recently, peroxisome proliferator-activated receptor-γ agonists (e.g., rosiglitazone) have been reported to ameliorate the senescence-like phenotype by modulating inflammatory mediator production. This study examined synergistic effects on the an...

Alternative Titles

Full title

Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2353920820

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2353920820

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-019-04025-8

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