Proteomic profiling of precipitated Clostridioides difficile toxin A and B antibodies
Proteomic profiling of precipitated Clostridioides difficile toxin A and B antibodies
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Contents
Highlights•Anti-toxin A and B Igs purified from sera after C. difficile infection or vaccination. •Proteomes of secreted anti-toxin Igs analysed by mass spectrometric sequencing. •Anti-toxin A and B Igs express convergent antibody responses in unrelated individuals. •Vaccination elicits similar IgV subfamily usage to natural infection.
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Full title
Proteomic profiling of precipitated Clostridioides difficile toxin A and B antibodies
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TN_cdi_proquest_journals_2353953313
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2353953313
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2019.10.096
