Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer
Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer
About this item
Full title
Author / Creator
Murthy, Rashmi K , Loi, Sherene , Okines, Alicia , Paplomata, Elisavet , Hamilton, Erika , Hurvitz, Sara A , Lin, Nancy U , Borges, Virginia , Abramson, Vandana , Anders, Carey , Bedard, Philippe L , Oliveira, Mafalda , Jakobsen, Erik , Bachelot, Thomas , Shachar, Shlomit S , Müller, Volkmar , Braga, Sofia , Duhoux, Francois P , Greil, Richard , Cameron, David , Carey, Lisa A , Curigliano, Giuseppe , Gelmon, Karen , Hortobagyi, Gabriel , Krop, Ian , Loibl, Sibylle , Pegram, Mark , Slamon, Dennis , Palanca-Wessels, M. Corinna , Walker, Luke , Feng, Wentao and Winer, Eric P
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In women with HER2-positive metastatic breast cancer who had previously received HER2-targeted therapy, tucatinib, a new selective inhibitor of the HER2 tyrosine kinase, was added to trastuzumab and capecitabine and compared with trastuzumab and capecitabine plus placebo. Progression-free survival at 1 year was 33% with tucatinib and 12% with place...
Alternative Titles
Full title
Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer
Authors, Artists and Contributors
Author / Creator
Loi, Sherene
Okines, Alicia
Paplomata, Elisavet
Hamilton, Erika
Hurvitz, Sara A
Lin, Nancy U
Borges, Virginia
Abramson, Vandana
Anders, Carey
Bedard, Philippe L
Oliveira, Mafalda
Jakobsen, Erik
Bachelot, Thomas
Shachar, Shlomit S
Müller, Volkmar
Braga, Sofia
Duhoux, Francois P
Greil, Richard
Cameron, David
Carey, Lisa A
Curigliano, Giuseppe
Gelmon, Karen
Hortobagyi, Gabriel
Krop, Ian
Loibl, Sibylle
Pegram, Mark
Slamon, Dennis
Palanca-Wessels, M. Corinna
Walker, Luke
Feng, Wentao
Winer, Eric P
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2354258648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2354258648
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1914609
