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Circulating intranuclear proteins may play a role in development of disseminated intravascular coagu...

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2356403195

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia

About this item

Full title

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia

Publisher

Singapore: Springer Singapore

Journal title

International journal of hematology, 2020-03, Vol.111 (3), p.378-387

Language

English

Formats

Publication information

Publisher

Singapore: Springer Singapore

More information

Scope and Contents

Contents

Intranuclear proteins, including high mobility group box 1 (HMGB1) and histone H3, released from inflammatory cells activate platelets and the coagulation systems, leading to development of disseminated intravascular coagulation (DIC) in individuals with sepsis. These observations prompted us to hypothesize that HMGB1 and histone H3 liberated from...

Alternative Titles

Full title

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2356403195

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2356403195

Other Identifiers

ISSN

0925-5710

E-ISSN

1865-3774

DOI

10.1007/s12185-019-02798-5

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