Systemic L-Citrulline Prevents Cerebral Vasospasm in Haptoglobin 2-2 Transgenic Mice After Subarachn...
Systemic L-Citrulline Prevents Cerebral Vasospasm in Haptoglobin 2-2 Transgenic Mice After Subarachnoid Hemorrhage
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Hagerstown, MD: Oxford University Press
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English
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Hagerstown, MD: Oxford University Press
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Abstract
Background:
Nitric oxide (NO) depletion and periadventitial inflammation contribute to the pathogenesis of cerebral vasospasm. L-Citrulline increases L-arginine levels, thereby raising NO synthesis. Transgenic C57BI6 mice with a haptoglobin (Hp) 2-2 genotype develop more severe vasospasm than wild-type (Hp 1–1) mice after subarachnoi...
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Full title
Systemic L-Citrulline Prevents Cerebral Vasospasm in Haptoglobin 2-2 Transgenic Mice After Subarachnoid Hemorrhage
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TN_cdi_proquest_journals_2356834777
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2356834777
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ISSN
0148-396X
E-ISSN
1524-4040
DOI
10.1227/NEU.0b013e3182363c2f
