APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers
APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Background & Aims: WNT activation is a hallmark of colorectal cancer. BRAF mutation is present in 15% of colorectal cancers, and the role of mutations in WNT signaling regulators in this context is unclear. Here we evaluate the mutational landscape of WNT signaling regulators in BRAF mutant cancers. Methods: We performed exome-sequencing on 24 BRAF...
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Full title
APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers
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TN_cdi_proquest_journals_2360505614
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2360505614
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E-ISSN
2692-8205
DOI
10.1101/2020.02.16.942904
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https://www.proquest.com/docview/2360505614?pq-origsite=primo&accountid=13902
