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Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial...

Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_236155925

Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial infarction

About this item

Full title

Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial infarction

Publisher

Boston: Boston : Springer US

Journal title

Apoptosis (London), 2009-06, Vol.14 (6), p.753-763

Language

English

Formats

Publication information

Publisher

Boston: Boston : Springer US

More information

Scope and Contents

Contents

During acute myocardial infarction (AMI), ischemia leads to necrotic areas surrounded by border zones of reversibly damaged cardiomyocytes, showing membrane flip-flop. During reperfusion type IIA secretory phopholipase A₂ (sPLA₂-IIA) induces direct cell-toxicity and facilitates binding of other inflammatory mediators on these cardiomyocytes. Theref...

Alternative Titles

Full title

Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial infarction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_236155925

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_236155925

Other Identifiers

ISSN

1360-8185

E-ISSN

1573-675X

DOI

10.1007/s10495-009-0350-x

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