Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial...
Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial infarction
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Publisher
Boston: Boston : Springer US
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Language
English
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Publisher
Boston: Boston : Springer US
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Contents
During acute myocardial infarction (AMI), ischemia leads to necrotic areas surrounded by border zones of reversibly damaged cardiomyocytes, showing membrane flip-flop. During reperfusion type IIA secretory phopholipase A₂ (sPLA₂-IIA) induces direct cell-toxicity and facilitates binding of other inflammatory mediators on these cardiomyocytes. Theref...
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Full title
Inhibition of type 2A secretory phospholipase A₂ reduces death of cardiomyocytes in acute myocardial infarction
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TN_cdi_proquest_journals_236155925
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_236155925
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ISSN
1360-8185
E-ISSN
1573-675X
DOI
10.1007/s10495-009-0350-x