Ciliation of muscle stem cells is critical to maintain regenerative capacity and is lost during agin...
Ciliation of muscle stem cells is critical to maintain regenerative capacity and is lost during aging
About this item
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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During aging, the regenerative capacity of muscle stem cells (MuSCs) decreases, diminishing the ability of muscle to repair following injury. We performed a small molecule library screen and discovered that the proliferation and expansion of aged MuSCs is regulated by signal transduction pathways organized by the primary cilium, a cellular protrusi...
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Full title
Ciliation of muscle stem cells is critical to maintain regenerative capacity and is lost during aging
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TN_cdi_proquest_journals_2380449024
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2380449024
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E-ISSN
2692-8205
DOI
10.1101/2020.03.20.000943
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https://www.proquest.com/docview/2380449024?pq-origsite=primo&accountid=13902
