Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor
Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The β1-adrenoceptor (β1AR) is a G protein-coupled receptor (GPCR) activated by the hormone noradrenaline, resulting in the coupling of the heterotrimeric G protein Gs1. G protein-mediated signalling is terminated by phosphorylation of the receptor C-terminus and coupling of β-arrestin 1 (βarr1, also known as arrestin-2), which displaces Gs and indu...
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Full title
Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor
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TN_cdi_proquest_journals_2384096460
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2384096460
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E-ISSN
2692-8205
DOI
10.1101/2020.03.27.011585
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https://www.proquest.com/docview/2384096460?pq-origsite=primo&accountid=13902
