A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules
A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules
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Author / Creator
Karki, Menuka , Jangid, Rahul K , Seervai, Riyad Nh , Jean-Philippe Bertocchio , Hotta, Takashi , Msaouel, Pavlos , Jung, Sung Y , Grimm, Sandra L , Coarfa, Cristian , Weissman, Bernard E , Ohi, Ryoma , Verhey, Kristen J , Hodges, Courtney H , Dere, Ruhee , Park, In-Young , Rathmell, Kimryn W , Walker, Cheryl L and Tripathi, Durga N
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
The chromatin modifier SETD2 was recently shown to be a dual-function methyltransferase that writes methyl marks on both chromatin and the mitotic spindle, revealing a-tubulin methylation as a new posttranslational modification of microtubules. Here, we report the first cytoskeletal reader for this SETD2 methyl mark: the polybromo protein PBRM1. We...
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Full title
A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules
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TN_cdi_proquest_journals_2393244108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2393244108
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E-ISSN
2692-8205
DOI
10.1101/2020.04.21.053942
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https://www.proquest.com/docview/2393244108?pq-origsite=primo&accountid=13902
