Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies new candidate su...
Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies new candidate susceptibility genes for breast and ovarian cancer
About this item
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Author / Creator
Kar, Siddhartha , Considine, Daniel , Tyrer, Jonathan , Plummer, Jasmine , Chen, Stephanie , Dezem, Felipe , Barbeira, Alvaro , Rajagopal, Padma , Rosenow, Will , Anton, Fernando , Bodelon, Clara , Chang-Claude, Jenny , Chenevix-Trench, Georgia , Defazio, Anna , Doerk, Thilo , Ekici, Arif , Ewing, Ailith , Fountzilas, George , Goode, Ellen , Hartman, Mikael , Heitz, Florian , Hillemanns, Peter , Hogdall, Estrid , Hogdall, Claus , Huzarski, Tomasz , Jensen, Allan , Karlan, Beth , Khusnutdinova, Elza , Kiemeney, Lambertus , Kjaer, Susanne , Klapdor, Rudiger , Kobel, Martin , Li, Jingmei , Liebrich, Clemens , May, Taymaa , Olsson, Hakan , Permuth, Jennifer , Peterlongo, Paolo , Radice, Paolo , Ramus, Susan , Riggan, Marjorie , Saloustros, Emmanouil , Simard, Jacques , Szafron, Lukasz , Thompson, Cheryl , Vierkant, Robert , Winham, Stacey , Zheng, Wei , Doherty, Jennifer , Berchuck, Andrew , Lawrenson, Kate , Im, Hae , Manichaikul, Ani , Pharoah, Paul , Gayther, Simon and Schildkraut, Joellen
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Familial, genome-wide association (GWAS), and sequencing studies and genetic correlation analyses have progressively unraveled the shared or pleiotropic germline genetics of breast and ovarian cancer. In this study, we aimed to leverage this shared germline genetics to improve the power of transcriptome-wide association studies (TWAS) to identify c...
Alternative Titles
Full title
Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies new candidate susceptibility genes for breast and ovarian cancer
Authors, Artists and Contributors
Author / Creator
Considine, Daniel
Tyrer, Jonathan
Plummer, Jasmine
Chen, Stephanie
Dezem, Felipe
Barbeira, Alvaro
Rajagopal, Padma
Rosenow, Will
Anton, Fernando
Bodelon, Clara
Chang-Claude, Jenny
Chenevix-Trench, Georgia
Defazio, Anna
Doerk, Thilo
Ekici, Arif
Ewing, Ailith
Fountzilas, George
Goode, Ellen
Hartman, Mikael
Heitz, Florian
Hillemanns, Peter
Hogdall, Estrid
Hogdall, Claus
Huzarski, Tomasz
Jensen, Allan
Karlan, Beth
Khusnutdinova, Elza
Kiemeney, Lambertus
Kjaer, Susanne
Klapdor, Rudiger
Kobel, Martin
Li, Jingmei
Liebrich, Clemens
May, Taymaa
Olsson, Hakan
Permuth, Jennifer
Peterlongo, Paolo
Radice, Paolo
Ramus, Susan
Riggan, Marjorie
Saloustros, Emmanouil
Simard, Jacques
Szafron, Lukasz
Thompson, Cheryl
Vierkant, Robert
Winham, Stacey
Zheng, Wei
Doherty, Jennifer
Berchuck, Andrew
Lawrenson, Kate
Im, Hae
Manichaikul, Ani
Pharoah, Paul
Gayther, Simon
Schildkraut, Joellen
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2394462764
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2394462764
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.04.23.043653
How to access this item
https://www.proquest.com/docview/2394462764?pq-origsite=primo&accountid=13902
