Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis
Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Reverse transcription, an essential event in the HIV-1 lifecycle, requires deoxynucleotide triphosphates (dNTPs) to fuel DNA synthesis, thus requiring penetration of dNTPs into the viral core. The central cavity of the capsid protein (CA) hexamer reveals itself as a plausible channel that allows the passage of dNTPs into assembled capsids. Neverthe...
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Full title
Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis
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TN_cdi_proquest_journals_2397149538
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2397149538
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E-ISSN
2692-8205
DOI
10.1101/2020.04.30.071217
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https://www.proquest.com/docview/2397149538?pq-origsite=primo&accountid=13902
