Kinetics of Internalization and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugate in Human Leuk...
Kinetics of Internalization and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugate in Human Leukemia Cell Line, K562
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Oxford, UK: Blackwell Publishing Ltd
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English
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Oxford, UK: Blackwell Publishing Ltd
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ABSTRACT
Human serum transferrin was conjugated with an anticancer‐active polypeptide, neocarzinostatin, by using N‐succinimidy1‐3‐(2‐pyridyldithio)propionate. The conjugate consisted of 1.8 mol of neocarzinostatin per 1 mol of transferrin on average and retained cytotoxic activity against human tumor cells. This conjugate was capable of binding...
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Full title
Kinetics of Internalization and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugate in Human Leukemia Cell Line, K562
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TN_cdi_proquest_journals_2400101045
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2400101045
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ISSN
0910-5050,1347-9032
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.1990.tb02512.x
