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Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells

Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2400239353

Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells

About this item

Full title

Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The paired measurement of RNA and surface protein abundance in single cells with CITE-seq is a promising approach to connect transcriptional variation with cell phenotypes and functions. However, each data modality exhibits unique technical biases, making it challenging to conduct a joint analysis and combine these two views into a unified represen...

Alternative Titles

Full title

Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2400239353

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2400239353

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.05.08.083337