Antibody-mediated delivery of LIGHT to the tumor boosts Natural Killer cells and delays tumor progre...
Antibody-mediated delivery of LIGHT to the tumor boosts Natural Killer cells and delays tumor progression
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Background: LIGHT is a member of the TNF superfamily, which has been claimed to mediate anti-tumor activity on the basis of cancer cures observed in immunocompetent mice bearing transgenic LIGHT-expressing tumors. The preclinical development of a LIGHT-based therapeutic has been hindered by the lack of functional stability exhibited by this protein...
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Antibody-mediated delivery of LIGHT to the tumor boosts Natural Killer cells and delays tumor progression
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TN_cdi_proquest_journals_2400239912
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2400239912
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E-ISSN
2692-8205
DOI
10.1101/2020.05.08.084277
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https://www.proquest.com/docview/2400239912?pq-origsite=primo&accountid=13902