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Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degra...

Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2400239997

Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degrading enzyme, in brain

About this item

Full title

Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degrading enzyme, in brain

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Alzheimer's disease (AD) brains are characterized by increased levels of the pathogenic amyloid beta (Abeta) peptide, which accumulates into extracellular plaques. Finding a way to lower Abeta levels is fundamental for the prevention and treatment of AD. Neprilysin is the major Abeta-degrading enzyme which is regulated by the neuropeptide somatosta...

Alternative Titles

Full title

Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degrading enzyme, in brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2400239997

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2400239997

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.05.09.085795