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Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological c...

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2402633674

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions

About this item

Full title

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Cyclin dependent kinase 5 (Cdk5) regulates various developmental and physiological processes in the central nervous system. Deregulation of Cdk5 activity in neurons induces severe neurodegeneration and has been implicated in Alzheimers disease (AD) and other neurodegenerative conditions. A large fraction of AD risk genes are highly expressed in mic...

Alternative Titles

Full title

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2402633674

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2402633674

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.05.12.090605