Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Synaptic loss, neuronal death, and circuit remodeling are common features of central nervous system neurodegenerative disorders. Retinitis pigmentosa (RP), the leading cause of inherited blindness, is a group of retinal dystrophies characterized by photoreceptor dysfunction and death. The insulin receptor, a key controller of metabolism, also regul...
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Full title
Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
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TN_cdi_proquest_journals_2402635681
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2402635681
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E-ISSN
2692-8205
DOI
10.1101/2020.05.13.092833
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https://www.proquest.com/docview/2402635681?pq-origsite=primo&accountid=13902
