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Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2402810155

Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

About this item

Full title

Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2020-04, Vol.94 (4), p.1151-1172

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Adverse outcome pathways (AOPs) have been recently introduced as tools to map the mechanisms underlying toxic events relevant for chemical risk assessment. AOPs particularly depict the linkage between a molecular initiating event and an adverse outcome through a number of intermediate key events. An AOP has been previously introduced for cholestati...

Alternative Titles

Full title

Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2402810155

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2402810155

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-020-02691-9

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